# Reduced Radiotherapy With Pac/Cis vs Standard Radiotherapy With 5-FU/Cis in Locally Advanced Head and Neck Cancer

> **NCT01126216** · PHASE3 · TERMINATED · sponsor: **University of Erlangen-Nürnberg Medical School** · enrollment: 221 (actual)

## Conditions studied

- Head and Neck Cancer

## Interventions

- **DRUG:** Paclitaxel/Cisplatin
- **RADIATION:** Reduced RT
- **DRUG:** 5-FU/Cisplatin
- **RADIATION:** Standard RT

## Key facts

- **NCT ID:** NCT01126216
- **Lead sponsor:** University of Erlangen-Nürnberg Medical School
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2010-06
- **Primary completion:** 2015-06
- **Final completion:** 2019-06
- **Target enrollment:** 221 (ACTUAL)
- **Why stopped:** After an Interims analysis the Data Safety Monitoring board recommended this because no significant difference between the two arms was seen and was not expected with an reasonable recruitment of patients.

No interruptions of the trial were made.
- **Last updated:** 2021-05-04

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01126216

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01126216, "Reduced Radiotherapy With Pac/Cis vs Standard Radiotherapy With 5-FU/Cis in Locally Advanced Head and Neck Cancer". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT01126216. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*