# Bioequivalence Study of Generic Tretinoin 0.1% Microsphere Gel, 0.1% Retin-A Micro® and Placebo

> **NCT01135069** · PHASE3 · COMPLETED · sponsor: **Spear Pharmaceuticals** · enrollment: 480 (actual)

## Conditions studied

- Acne

## Interventions

- **DRUG:** Tretinoin microsphere 0.1%
- **DRUG:** Brand Retin-A Micro tretinoin microsphere gel 0.1%
- **DRUG:** placebo microsphere gel

## Key facts

- **NCT ID:** NCT01135069
- **Lead sponsor:** Spear Pharmaceuticals
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2009-10
- **Primary completion:** 2010-04
- **Final completion:** 2010-04
- **Target enrollment:** 480 (ACTUAL)
- **Last updated:** 2014-10-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01135069

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01135069, "Bioequivalence Study of Generic Tretinoin 0.1% Microsphere Gel, 0.1% Retin-A Micro® and Placebo". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT01135069. Licensed CC0.

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