# Probiotic Saccharomyces Boulardii for the Prevention of Antibiotic-associated Diarrhoea

> **NCT01143272** · PHASE3 · TERMINATED · sponsor: **Bernhard Nocht Institute for Tropical Medicine** · enrollment: 477 (actual)

## Conditions studied

- Antibiotic-associated Diarrhea
- Clostridium Difficile
- Diarrhea

## Interventions

- **DRUG:** Saccharomyces boulardii
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT01143272
- **Lead sponsor:** Bernhard Nocht Institute for Tropical Medicine
- **Sponsor class:** OTHER_GOV
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2010-06
- **Primary completion:** 2012-10
- **Final completion:** 2012-10
- **Target enrollment:** 477 (ACTUAL)
- **Why stopped:** Masked independent interim analysis: completion of the trial was unlikely.
- **Last updated:** 2016-07-18

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01143272

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01143272, "Probiotic Saccharomyces Boulardii for the Prevention of Antibiotic-associated Diarrhoea". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT01143272. Licensed CC0.

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