# T-Regulatory Cell and CD3 Depleted Double Umbilical Cord Blood Transplantation in Hematologic Malignancies

> **NCT01163201** · PHASE1,PHASE2 · WITHDRAWN · sponsor: **Masonic Cancer Center, University of Minnesota**

## Conditions studied

- Hematologic Malignancy
- Acute Myeloid Leukemia
- Acute Lymphocytic Leukemia
- Chronic Myelogenous Leukemia in Blast Crisis
- Anemia, Refractory, With Excess of Blasts
- Chronic Myeloproliferative Disease
- Chronic Lymphocytic Leukemia
- Small Lymphocytic Lymphoma
- Marginal Zone B-cell Lymphoma
- Follicular Lymphoma
- Lymphoplasmacytic Lymphoma
- Mantle-Cell Lymphoma
- Prolymphocytic Lymphoma
- Large Cell Non-Hodgkin's Lymphoma
- Lymphoblastic Lymphoma
- Burkitt's Lymphoma
- High Grade Non-Hodgkin's Lymphoma

## Interventions

- **BIOLOGICAL:** Treg cells
- **BIOLOGICAL:** CD3+ Teff cells
- **DRUG:** Fludarabine
- **DRUG:** Cyclophosphamide
- **RADIATION:** Total body irradiation
- **BIOLOGICAL:** Umbilical cord blood transplantation

## Key facts

- **NCT ID:** NCT01163201
- **Lead sponsor:** Masonic Cancer Center, University of Minnesota
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2014-01
- **Primary completion:** 2015-01
- **Final completion:** 2015-01
- **Target enrollment:** 0 (ACTUAL)
- **Why stopped:** Replaced by a new study
- **Last updated:** 2017-12-02


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01163201

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01163201, "T-Regulatory Cell and CD3 Depleted Double Umbilical Cord Blood Transplantation in Hematologic Malignancies". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT01163201. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*