# Bupropion and Specific Cardiovascular Malformations

> **NCT01165255** · — · COMPLETED · sponsor: **GlaxoSmithKline** · enrollment: 7005 (actual)

## Conditions studied

- Depressive Disorder
- Pregnancy
- Smoking Cessation

## Interventions

- **DRUG:** 3. Exposure to other antidepressants during the first trimester comparison cohort
- **DRUG:** 2. Exposure to bupropion outside the first trimester comparison cohort
- **DRUG:** 1. Exposure to bupropion during the first trimester

## Key facts

- **NCT ID:** NCT01165255
- **Lead sponsor:** GlaxoSmithKline
- **Sponsor class:** INDUSTRY
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** COMPLETED
- **Start date:** 2010-06
- **Primary completion:** 2010-12
- **Final completion:** 2010-12
- **Target enrollment:** 7005 (ACTUAL)
- **Last updated:** 2017-06-07


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01165255

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01165255, "Bupropion and Specific Cardiovascular Malformations". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT01165255. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*