# Cilengitide in Combination With Irradiation in Children With Diffuse Intrinsic Pontine Glioma

> **NCT01165333** · PHASE1 · COMPLETED · sponsor: **Centre Oscar Lambret** · enrollment: 32 (actual)

## Conditions studied

- Diffuse Intrinsic Pontine Glioma

## Interventions

- **DRUG:** Cilengitide dose escalation
- **DRUG:** Cilengitide
- **RADIATION:** Concomitant radiotherapy
- **BIOLOGICAL:** Pharmacokinetic
- **BIOLOGICAL:** Pharmacogenetic
- **BIOLOGICAL:** Exploratory investigation

## Key facts

- **NCT ID:** NCT01165333
- **Lead sponsor:** Centre Oscar Lambret
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2010-09-06
- **Primary completion:** 2014-01
- **Final completion:** 2015-03
- **Target enrollment:** 32 (ACTUAL)
- **Last updated:** 2026-03-16


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01165333

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01165333, "Cilengitide in Combination With Irradiation in Children With Diffuse Intrinsic Pontine Glioma". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT01165333. Licensed CC0.

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