# Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells

> **NCT01174108** · PHASE2 · RECRUITING · sponsor: **National Heart, Lung, and Blood Institute (NHLBI)** · enrollment: 120 (estimated)

## Conditions studied

- Severe Aplastic Anemia
- MDS (Myelodysplastic Syndrome)

## Interventions

- **DEVICE:** Miltenyi CD34 Reagent System
- **OTHER:** Donor derived G-CSF mobilized PBC

## Key facts

- **NCT ID:** NCT01174108
- **Lead sponsor:** National Heart, Lung, and Blood Institute (NHLBI)
- **Sponsor class:** NIH
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2010-12-10
- **Primary completion:** 2027-12-30
- **Final completion:** 2028-06-30
- **Target enrollment:** 120 (ESTIMATED)
- **Last updated:** 2026-01-08


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01174108

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01174108, "Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT01174108. Licensed CC0.

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