# High-flow Conditioned Oxygen Therapy Versus Non-invasive Ventilation: Prevention of Post-extubation Failure

> **NCT01191489** · PHASE3 · COMPLETED · sponsor: **Hospital Infanta Sofia** · enrollment: 1042 (actual)

## Conditions studied

- Post-extubation Respiratory Failure

## Interventions

- **DEVICE:** High Flow Conditioned Oxygen Therapy in High Risk Patients
- **DEVICE:** Non-invasive mechanical ventilation
- **DEVICE:** Conventional Oxygen Therapy

## Key facts

- **NCT ID:** NCT01191489
- **Lead sponsor:** Hospital Infanta Sofia
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2012-09
- **Primary completion:** 2014-09
- **Final completion:** 2014-09
- **Target enrollment:** 1042 (ACTUAL)
- **Last updated:** 2014-09-12


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01191489

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01191489, "High-flow Conditioned Oxygen Therapy Versus Non-invasive Ventilation: Prevention of Post-extubation Failure". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT01191489. Licensed CC0.

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