# A Study of the Effect of Memantine on Pharmacokinetics, Safety and Tolerability of Single Dose RO5313534 in Healthy Volunteers, and the Effect of RO5313534 on Safety and Tolerability of Steady State Memantine

> **NCT01196065** · PHASE1 · COMPLETED · sponsor: **Hoffmann-La Roche** · enrollment: 16 (actual)

## Conditions studied

- Healthy Volunteer

## Interventions

- **DRUG:** RO5313534
- **DRUG:** memantine

## Key facts

- **NCT ID:** NCT01196065
- **Lead sponsor:** Hoffmann-La Roche
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2010-09
- **Primary completion:** —
- **Final completion:** 2010-11
- **Target enrollment:** 16 (ACTUAL)
- **Last updated:** 2016-11-02


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01196065

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01196065, "A Study of the Effect of Memantine on Pharmacokinetics, Safety and Tolerability of Single Dose RO5313534 in Healthy Volunteers, and the Effect of RO5313534 on Safety and Tolerability of Steady State Memantine". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT01196065. Licensed CC0.

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