# Radiation Therapy, Paclitaxel, and Carboplatin With or Without Trastuzumab in Treating Patients With Esophageal Cancer

> **NCT01196390** · PHASE3 · COMPLETED · sponsor: **National Cancer Institute (NCI)** · enrollment: 203 (actual)

## Conditions studied

- Esophageal Adenocarcinoma
- Gastroesophageal Junction Adenocarcinoma
- Stage IB Esophageal Cancer AJCC v7
- Stage IIA Esophageal Cancer AJCC v7
- Stage IIB Esophageal Cancer AJCC v7
- Stage IIIA Esophageal Cancer AJCC v7
- Stage IIIB Esophageal Cancer AJCC v7

## Interventions

- **DRUG:** Carboplatin
- **OTHER:** Laboratory Biomarker Analysis
- **DRUG:** Paclitaxel
- **OTHER:** Quality-of-Life Assessment
- **RADIATION:** Radiation Therapy
- **PROCEDURE:** Therapeutic Conventional Surgery
- **BIOLOGICAL:** Trastuzumab

## Key facts

- **NCT ID:** NCT01196390
- **Lead sponsor:** National Cancer Institute (NCI)
- **Sponsor class:** NIH
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2011-02-14
- **Primary completion:** 2019-12-23
- **Final completion:** 2023-08-15
- **Target enrollment:** 203 (ACTUAL)
- **Last updated:** 2026-02-18

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01196390

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01196390, "Radiation Therapy, Paclitaxel, and Carboplatin With or Without Trastuzumab in Treating Patients With Esophageal Cancer". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT01196390. Licensed CC0.

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