# Irinotecan Hydrochloride, Fluorouracil, and Leucovorin Calcium With or Without Zibotentan in Treating Patients With Metastatic Colorectal Cancer

> **NCT01205711** · PHASE2 · COMPLETED · sponsor: **Cardiff University** · enrollment: 111 (actual)

## Conditions studied

- Colorectal Cancer

## Interventions

- **DRUG:** FOLFIRI regimen
- **DRUG:** fluorouracil
- **DRUG:** irinotecan hydrochloride
- **DRUG:** leucovorin calcium
- **DRUG:** zibotentan
- **OTHER:** laboratory biomarker analysis
- **OTHER:** pharmacogenomic studies

## Key facts

- **NCT ID:** NCT01205711
- **Lead sponsor:** Cardiff University
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2010-04
- **Primary completion:** 2011-07
- **Final completion:** 2012-09
- **Target enrollment:** 111 (ACTUAL)
- **Last updated:** 2014-07-08


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01205711

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01205711, "Irinotecan Hydrochloride, Fluorouracil, and Leucovorin Calcium With or Without Zibotentan in Treating Patients With Metastatic Colorectal Cancer". Retrieved via AI Analytics 2026-07-26 from https://api.ai-analytics.org/clinical/NCT01205711. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*