# Sirolimus In Autosomal Dominant Polycystic Kidney Disease And Severe Renal Insufficiency

> **NCT01223755** · PHASE2,PHASE3 · TERMINATED · sponsor: **Mario Negri Institute for Pharmacological Research** · enrollment: 41 (actual)

## Conditions studied

- Autosomal Dominant Polycystic Kidney Disease (ADPKD)

## Interventions

- **DRUG:** Sirolimus
- **DRUG:** conventional therapy

## Key facts

- **NCT ID:** NCT01223755
- **Lead sponsor:** Mario Negri Institute for Pharmacological Research
- **Sponsor class:** OTHER
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2010-09
- **Primary completion:** 2012-07
- **Final completion:** 2012-07
- **Target enrollment:** 41 (ACTUAL)
- **Why stopped:** safety and efficacy reason
- **Last updated:** 2013-02-25


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01223755

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01223755, "Sirolimus In Autosomal Dominant Polycystic Kidney Disease And Severe Renal Insufficiency". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT01223755. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*