# Study of Different Formulations of a Clostridium Difficile Toxoid Vaccine Given at Three Different Schedules in Adults

> **NCT01230957** · PHASE2 · COMPLETED · sponsor: **Sanofi Pasteur, a Sanofi Company** · enrollment: 650 (actual)

## Conditions studied

- Clostridium Difficile Infection
- Diarrhea

## Interventions

- **BIOLOGICAL:** Clostridium difficile toxoids A and B (Low-dose with adjuvant)
- **BIOLOGICAL:** Clostridium difficile toxoids A and B (Low-dose without adjuvant)
- **BIOLOGICAL:** Clostridium difficile toxoids A and B (high-dose with adjuvant)
- **BIOLOGICAL:** Clostridium difficile toxoids A and B (high-dose without adjuvant)
- **BIOLOGICAL:** Placebo: 0.9% normal saline
- **BIOLOGICAL:** Clostridium difficile toxoids A and B (high-dose with adjuvant)
- **BIOLOGICAL:** Clostridium difficile toxoids A and B (high-dose with adjuvant)

## Key facts

- **NCT ID:** NCT01230957
- **Lead sponsor:** Sanofi Pasteur, a Sanofi Company
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2010-10
- **Primary completion:** 2012-11
- **Final completion:** 2013-03
- **Target enrollment:** 650 (ACTUAL)
- **Last updated:** 2018-07-18


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01230957

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01230957, "Study of Different Formulations of a Clostridium Difficile Toxoid Vaccine Given at Three Different Schedules in Adults". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT01230957. Licensed CC0.

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