# Bafetinib in Treating Patients With Recurrent High-Grade Glioma or Brain Metastases

> **NCT01234740** · PHASE1 · COMPLETED · sponsor: **City of Hope Medical Center** · enrollment: 7 (actual)

## Conditions studied

- Adult Anaplastic Astrocytoma
- Adult Anaplastic Ependymoma
- Adult Anaplastic Oligodendroglioma
- Adult Giant Cell Glioblastoma
- Adult Glioblastoma
- Adult Gliosarcoma
- Adult Mixed Glioma
- Recurrent Adult Brain Tumor
- Tumors Metastatic to Brain
- Adult Anaplastic Oligoastrocytoma

## Interventions

- **DRUG:** bafetinib
- **PROCEDURE:** microdialysis
- **OTHER:** pharmacological study
- **OTHER:** liquid chromatography
- **OTHER:** mass spectrometry
- **OTHER:** laboratory biomarker analysis
- **GENETIC:** protein expression analysis
- **GENETIC:** western blotting
- **OTHER:** immunohistochemistry staining method
- **PROCEDURE:** therapeutic conventional surgery

## Key facts

- **NCT ID:** NCT01234740
- **Lead sponsor:** City of Hope Medical Center
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2010-12
- **Primary completion:** 2013-03
- **Final completion:** 2013-03
- **Target enrollment:** 7 (ACTUAL)
- **Last updated:** 2018-04-17

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01234740

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01234740, "Bafetinib in Treating Patients With Recurrent High-Grade Glioma or Brain Metastases". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT01234740. Licensed CC0.

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