# Preservative-Free Tafluprost (MK-2452) for the Treatment of Open-Angle Glaucoma or Ocular Hypertension (MK-2452-002)

> **NCT01254604** · PHASE3 · COMPLETED · sponsor: **Merck Sharp & Dohme LLC** · enrollment: 190 (actual)

## Conditions studied

- Glaucoma
- Ocular Hypertension

## Interventions

- **DRUG:** Preservative-Free Tafluprost or vehicle
- **DRUG:** Preservative-Free Timolol maleate

## Key facts

- **NCT ID:** NCT01254604
- **Lead sponsor:** Merck Sharp & Dohme LLC
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2011-12-01
- **Primary completion:** 2013-05-09
- **Final completion:** 2013-05-09
- **Target enrollment:** 190 (ACTUAL)
- **Last updated:** 2018-09-20


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01254604

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01254604, "Preservative-Free Tafluprost (MK-2452) for the Treatment of Open-Angle Glaucoma or Ocular Hypertension (MK-2452-002)". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT01254604. Licensed CC0.

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