# Lenalidomide and Cetuximab in Treating Patients With Advanced Colorectal Cancer or Head and Neck Cancer

> **NCT01254617** · PHASE1 · COMPLETED · sponsor: **National Cancer Institute (NCI)** · enrollment: 24 (actual)

## Conditions studied

- Recurrent Colon Carcinoma
- Recurrent Hypopharyngeal Squamous Cell Carcinoma
- Recurrent Laryngeal Squamous Cell Carcinoma
- Recurrent Laryngeal Verrucous Carcinoma
- Recurrent Lip and Oral Cavity Squamous Cell Carcinoma
- Recurrent Metastatic Squamous Cell Carcinoma in the Neck With Occult Primary
- Recurrent Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma
- Recurrent Nasopharyngeal Keratinizing Squamous Cell Carcinoma
- Recurrent Oral Cavity Verrucous Carcinoma
- Recurrent Oropharyngeal Squamous Cell Carcinoma
- Recurrent Rectal Carcinoma
- Recurrent Salivary Gland Carcinoma
- Salivary Gland Squamous Cell Carcinoma
- Squamous Cell Carcinoma Metastatic in the Neck With Occult Primary
- Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7
- Stage IV Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7
- Stage IVA Colon Cancer AJCC v7
- Stage IVA Laryngeal Squamous Cell Carcinoma AJCC v7
- Stage IVA Laryngeal Verrucous Carcinoma AJCC v7
- Stage IVA Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7
- Stage IVA Major Salivary Gland Cancer AJCC v7
- Stage IVA Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v7
- Stage IVA Oral Cavity Cancer AJCC v6 and v7
- Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7
- Stage IVA Rectal Cancer AJCC v7
- Stage IVB Colon Cancer AJCC v7
- Stage IVB Laryngeal Squamous Cell Carcinoma AJCC v7
- Stage IVB Laryngeal Verrucous Carcinoma AJCC v7
- Stage IVB Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7
- Stage IVB Major Salivary Gland Cancer AJCC v7
- Stage IVB Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v7
- Stage IVB Oral Cavity Cancer AJCC v6 and v7
- Stage IVB Oropharyngeal Squamous Cell Carcinoma AJCC v7
- Stage IVB Rectal Cancer AJCC v7
- Stage IVC Laryngeal Squamous Cell Carcinoma AJCC v7
- Stage IVC Laryngeal Verrucous Carcinoma AJCC v7
- Stage IVC Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7
- Stage IVC Major Salivary Gland Cancer AJCC v7
- Stage IVC Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v7
- Stage IVC Oral Cavity Cancer AJCC v6 and v7
- Stage IVC Oropharyngeal Squamous Cell Carcinoma AJCC v7
- Tongue Carcinoma

## Interventions

- **BIOLOGICAL:** Cetuximab
- **OTHER:** Laboratory Biomarker Analysis
- **DRUG:** Lenalidomide

## Key facts

- **NCT ID:** NCT01254617
- **Lead sponsor:** National Cancer Institute (NCI)
- **Sponsor class:** NIH
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2011-02-10
- **Primary completion:** 2014-01-29
- **Final completion:** 2014-01-29
- **Target enrollment:** 24 (ACTUAL)
- **Last updated:** 2020-03-13


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01254617

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01254617, "Lenalidomide and Cetuximab in Treating Patients With Advanced Colorectal Cancer or Head and Neck Cancer". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT01254617. Licensed CC0.

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