# Influence of CYP3A4-induction by St. John's Wort on the Steady State Pharmacokinetics of Bosentan

> **NCT01258504** · — · COMPLETED · sponsor: **Gerd Mikus** · enrollment: 13 (actual)

## Conditions studied

- Drug Interactions

## Interventions

- **DRUG:** St. Johns Wort

## Key facts

- **NCT ID:** NCT01258504
- **Lead sponsor:** Gerd Mikus
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** COMPLETED
- **Start date:** 2011-01
- **Primary completion:** 2011-12
- **Final completion:** 2012-06
- **Target enrollment:** 13 (ACTUAL)
- **Last updated:** 2017-05-31


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01258504

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01258504, "Influence of CYP3A4-induction by St. John's Wort on the Steady State Pharmacokinetics of Bosentan". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT01258504. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
