# A Study of the Effect of Food on the Pharmacokinetics of Single Dose RO5185426 And the Safety And Efficacy of Continuous Administration in Patients With BRAF V600E Mutation-Positive Metastatic Melanoma

> **NCT01264380** · PHASE1 · COMPLETED · sponsor: **Hoffmann-La Roche** · enrollment: 16 (actual)

## Conditions studied

- Malignant Melanoma

## Interventions

- **DRUG:** RO5185426
- **DRUG:** RO5185426
- **DRUG:** RO5185426

## Key facts

- **NCT ID:** NCT01264380
- **Lead sponsor:** Hoffmann-La Roche
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2011-01
- **Primary completion:** 2013-05
- **Final completion:** 2013-05
- **Target enrollment:** 16 (ACTUAL)
- **Last updated:** 2016-11-02


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01264380

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01264380, "A Study of the Effect of Food on the Pharmacokinetics of Single Dose RO5185426 And the Safety And Efficacy of Continuous Administration in Patients With BRAF V600E Mutation-Positive Metastatic Melanoma". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT01264380. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*