# Clinical Trial Comparing Heparin and Protamine Fixed and Titrated Doses in Cardiac Surgery With Cardiopulmonary Bypass

> **NCT01267487** · PHASE4 · COMPLETED · sponsor: **SANE-Society of Anesthesiology** · enrollment: 240 (actual)

## Conditions studied

- Cardiac Surgery
- Cardiopulmonary Bypass
- Anticoagulation

## Interventions

- **DRUG:** Heparin fixed doses
- **DRUG:** PO continuous infusion of Protamine
- **DRUG:** Heparin and protamine titration

## Key facts

- **NCT ID:** NCT01267487
- **Lead sponsor:** SANE-Society of Anesthesiology
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2009-07
- **Primary completion:** 2010-03
- **Final completion:** 2010-11
- **Target enrollment:** 240 (ACTUAL)
- **Last updated:** 2010-12-28

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01267487

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01267487, "Clinical Trial Comparing Heparin and Protamine Fixed and Titrated Doses in Cardiac Surgery With Cardiopulmonary Bypass". Retrieved via AI Analytics 2026-06-04 from https://api.ai-analytics.org/clinical/NCT01267487. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*