Combination Chemotherapy and Bevacizumab With or Without RO4929097 in Treating Patients With Metastatic Colorectal Cancer

NCT01270438 · clinicaltrials.gov ↗

PHASE2

Phase

WITHDRAWN

Status

NIH

Sponsor class

Conditions

Adenocarcinoma of the Colon
Adenocarcinoma of the Rectum
Recurrent Colon Cancer
Recurrent Rectal Cancer
Stage IVA Colon Cancer
Stage IVA Rectal Cancer
Stage IVB Colon Cancer
Stage IVB Rectal Cancer

Interventions

DRUG: FOLFOX regimen
DRUG: gamma-secretase/Notch signalling pathway inhibitor RO4929097
BIOLOGICAL: bevacizumab
DRUG: oxaliplatin
DRUG: leucovorin calcium
DRUG: fluorouracil

Sponsor

National Cancer Institute (NCI)