# Aortic Stenosis and PhosphodiEsterase iNhibition With Aortic Valve Replacement (ASPEN-AVR): A Pilot Study

> **NCT01272388** · PHASE4 · TERMINATED · sponsor: **Washington University School of Medicine** · enrollment: 1 (actual)

## Conditions studied

- Aortic Stenosis

## Interventions

- **DRUG:** Tadalafil
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT01272388
- **Lead sponsor:** Washington University School of Medicine
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2011-01
- **Primary completion:** 2011-04
- **Final completion:** 2012-04
- **Target enrollment:** 1 (ACTUAL)
- **Why stopped:** We designed a different pilot trial based on data obtained after this study started - the 2 studies were too overlapping to continue both.
- **Last updated:** 2018-09-12


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01272388

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01272388, "Aortic Stenosis and PhosphodiEsterase iNhibition With Aortic Valve Replacement (ASPEN-AVR): A Pilot Study". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT01272388. Licensed CC0.

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