# A Trial of Oral BEZ235 and BKM120 in Combination With Paclitaxel With or Without Trastuzumab

> **NCT01285466** · PHASE1 · COMPLETED · sponsor: **Novartis Pharmaceuticals** · enrollment: 110 (actual)

## Conditions studied

- Metastatic or Locally Advanced Solid Tumors

## Interventions

- **DRUG:** BEZ235 + paclitaxel
- **DRUG:** BKM120 + paclitaxel
- **DRUG:** BEZ235 + paclitaxel + trastuzumab
- **DRUG:** BKM120 + paclitaxel + trastuzumab

## Key facts

- **NCT ID:** NCT01285466
- **Lead sponsor:** Novartis Pharmaceuticals
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2011-01
- **Primary completion:** 2014-10
- **Final completion:** 2014-10
- **Target enrollment:** 110 (ACTUAL)
- **Last updated:** 2020-12-09


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01285466

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01285466, "A Trial of Oral BEZ235 and BKM120 in Combination With Paclitaxel With or Without Trastuzumab". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT01285466. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*