Yttrium-90 Anti-CD45 Monoclonal Antibody BC8 Followed by Donor Stem Cell Transplant in Treating Patients With High-Risk AML, ALL, or MDS
Conditions
- Chronic Myelomonocytic Leukemia
- Previously Treated Myelodysplastic Syndrome
- Recurrent Adult Acute Lymphoblastic Leukemia
- Recurrent Adult Acute Myeloid Leukemia
- Refractory Anemia With Excess Blasts
- Secondary Acute Myeloid Leukemia
Interventions
- PROCEDURE: Allogeneic Bone Marrow Transplantation
- PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation
- DRUG: Cyclosporine
- DRUG: Fludarabine Phosphate
- BIOLOGICAL: Indium In 111 Anti-CD45 Monoclonal Antibody BC8
- OTHER: Laboratory Biomarker Analysis
- DRUG: Mycophenolate Mofetil
- PROCEDURE: Peripheral Blood Stem Cell Transplantation
- OTHER: Pharmacological Study
- RADIATION: Total-Body Irradiation
- RADIATION: Yttrium Y 90 Anti-CD45 Monoclonal Antibody BC8
Sponsor
Fred Hutchinson Cancer Center
Collaborators