# MK-0954E Study in Participants With Hypertension (MK-0954E-357)

> **NCT01302691** · PHASE3 · COMPLETED · sponsor: **Merck Sharp & Dohme LLC** · enrollment: 327 (actual)

## Conditions studied

- Hypertension

## Interventions

- **DRUG:** losartan potassium + hydrochlorothiazide + amlodipine besylate (MK-0954E)
- **DRUG:** Losartan potassium
- **DRUG:** Amlodipine besylate
- **DRUG:** Placebo to MK-0954E
- **DRUG:** Placebo to losartan potassium
- **DRUG:** Placebo to amlodipine besylate

## Key facts

- **NCT ID:** NCT01302691
- **Lead sponsor:** Merck Sharp & Dohme LLC
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2011-01-01
- **Primary completion:** 2012-04-01
- **Final completion:** 2012-04-01
- **Target enrollment:** 327 (ACTUAL)
- **Last updated:** 2019-03-15


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01302691

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01302691, "MK-0954E Study in Participants With Hypertension (MK-0954E-357)". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT01302691. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
