Combination Chemotherapy and Bevacizumab Before Surgery and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer

NCT01320683 · clinicaltrials.gov ↗

PHASE2

Phase

TERMINATED

Status

1

Enrollment

OTHER

Sponsor class

Stopped Slow accrual.

Conditions

Liver Metastases
Recurrent Colon Cancer
Recurrent Rectal Cancer
Stage IVA Colon Cancer
Stage IVA Rectal Cancer
Stage IVB Colon Cancer
Stage IVB Rectal Cancer

Interventions

DRUG: oxaliplatin
DRUG: leucovorin calcium
DRUG: fluorouracil
BIOLOGICAL: bevacizumab
RADIATION: yttrium Y 90 DOTA anti-CEA monoclonal antibody M5A
OTHER: laboratory biomarker analysis
OTHER: pharmacological study
DRUG: irinotecan hydrochloride

Sponsor

City of Hope Medical Center

Collaborators

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