# Everolimus, Erlotinib Hydrochloride, and Radiation Therapy in Treating Patients With Recurrent Head and Neck Cancer Previously Treated With Radiation Therapy

> **NCT01332279** · PHASE1 · WITHDRAWN · sponsor: **Fox Chase Cancer Center**

## Conditions studied

- Recurrent Metastatic Squamous Neck Cancer With Occult Primary
- Recurrent Salivary Gland Cancer
- Recurrent Squamous Cell Carcinoma of the Hypopharynx
- Recurrent Squamous Cell Carcinoma of the Larynx
- Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity
- Recurrent Squamous Cell Carcinoma of the Oropharynx
- Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity
- Recurrent Verrucous Carcinoma of the Larynx
- Recurrent Verrucous Carcinoma of the Oral Cavity
- Salivary Gland Squamous Cell Carcinoma
- Tongue Cancer

## Interventions

- **DRUG:** everolimus
- **DRUG:** erlotinib hydrochloride
- **PROCEDURE:** biopsy
- **OTHER:** laboratory biomarker analysis
- **OTHER:** immunohistochemistry staining method
- **GENETIC:** polyacrylamide gel electrophoresis
- **OTHER:** pharmacological study
- **RADIATION:** external beam radiation therapy
- **GENETIC:** microarray analysis

## Key facts

- **NCT ID:** NCT01332279
- **Lead sponsor:** Fox Chase Cancer Center
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2011-04
- **Primary completion:** 2011-05
- **Final completion:** 2011-05
- **Target enrollment:** 0 (ACTUAL)
- **Why stopped:** Pharmaceutical co. withdrew support. Study was never activated and did not accrue any patients.
- **Last updated:** 2023-04-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01332279

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01332279, "Everolimus, Erlotinib Hydrochloride, and Radiation Therapy in Treating Patients With Recurrent Head and Neck Cancer Previously Treated With Radiation Therapy". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT01332279. Licensed CC0.

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