Pilot Study of Leuprolide to Improve Immune Function After Allogeneic Bone Marrow Transplantation

NCT01338987 · clinicaltrials.gov ↗

PHASE2

Phase

COMPLETED

Status

76

Enrollment

NIH

Sponsor class

Conditions

Myelodysplastic Syndrome
Acute Lymphocytic Leukemia
Acute Myelogenous Leukemia
Chronic Myelogenous Leukemia
Chronic Myelomonocytic Leukemia

Interventions

PROCEDURE: First Allogeneic Bone Marrow Transplant (BMT)
DRUG: Leuprolide
DRUG: 18F FLT
DRUG: Cyclophosphamide
DRUG: Methotrexate
DRUG: Tacrolimus
RADIATION: Total Body Irradiation
DRUG: Busulfan
DRUG: Fludarabine
PROCEDURE: Second Allogeneic Bone Marrow Transplantation

Sponsor

National Cancer Institute (NCI)