# Comparison of Increasing Doses of Tapentadol Versus a Combination of Tapentadol and Pregabalin

> **NCT01352741** · PHASE4 · COMPLETED · sponsor: **Grünenthal GmbH** · enrollment: 622 (actual)

## Conditions studied

- Low Back Pain
- Neuropathic Pain

## Interventions

- **DRUG:** Tapentadol Prolonged Release
- **DRUG:** Tapentadol Prolonged Release with Pregabalin
- **DRUG:** Tapentadol Prolonged Release open label maintenance

## Key facts

- **NCT ID:** NCT01352741
- **Lead sponsor:** Grünenthal GmbH
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2011-03
- **Primary completion:** 2012-01
- **Final completion:** 2012-01
- **Target enrollment:** 622 (ACTUAL)
- **Last updated:** 2019-10-28


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01352741

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01352741, "Comparison of Increasing Doses of Tapentadol Versus a Combination of Tapentadol and Pregabalin". Retrieved via AI Analytics 2026-05-29 from https://api.ai-analytics.org/clinical/NCT01352741. Licensed CC0.

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