# Stroke Hyperglycemia Insulin Network Effort (SHINE) Trial

> **NCT01369069** · PHASE3 · COMPLETED · sponsor: **University of Virginia** · enrollment: 1151 (actual)

## Conditions studied

- Acute Ischemic Stroke
- Diabetes
- Hyperglycemia

## Interventions

- **DRUG:** IV insulin to maintain target glucose concentration of 80-130 mg/dL
- **DRUG:** Standard Care control - sliding scale insulin to keep glucose less than 180 mg/dL

## Key facts

- **NCT ID:** NCT01369069
- **Lead sponsor:** University of Virginia
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2012-04
- **Primary completion:** 2018-11-19
- **Final completion:** 2018-11-19
- **Target enrollment:** 1151 (ACTUAL)
- **Last updated:** 2019-12-23

## Collaborators

- [object Object]
- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01369069

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01369069, "Stroke Hyperglycemia Insulin Network Effort (SHINE) Trial". Retrieved via AI Analytics 2026-06-05 from https://api.ai-analytics.org/clinical/NCT01369069. Licensed CC0.

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