# An Explorative Trial to Evaluate the Pharmacodynamic Effect of SPD557 on Reflux Parameters in Refractory GERD Patients

> **NCT01370863** · PHASE2 · TERMINATED · sponsor: **Shire** · enrollment: 67 (actual)

## Conditions studied

- Gastroesophageal Reflux Disease

## Interventions

- **DRUG:** SPD557
- **DRUG:** placebo

## Key facts

- **NCT ID:** NCT01370863
- **Lead sponsor:** Shire
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2010-12-02
- **Primary completion:** 2012-05-29
- **Final completion:** 2012-05-29
- **Target enrollment:** 67 (ACTUAL)
- **Why stopped:** This study was terminated early due to recruitment difficulties. There were no safety concerns.
- **Last updated:** 2021-06-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01370863

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01370863, "An Explorative Trial to Evaluate the Pharmacodynamic Effect of SPD557 on Reflux Parameters in Refractory GERD Patients". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT01370863. Licensed CC0.

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