# Combination Trial of Pimasertib (MSC1936369B) With Temsirolimus

> **NCT01378377** · PHASE1 · TERMINATED · sponsor: **EMD Serono** · enrollment: 33 (actual)

## Conditions studied

- Advanced Solid Tumor

## Interventions

- **DRUG:** Pimasertib
- **DRUG:** Pimasertib
- **DRUG:** Temsirolimus
- **DRUG:** Temsirolimus

## Key facts

- **NCT ID:** NCT01378377
- **Lead sponsor:** EMD Serono
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2011-05-27
- **Primary completion:** 2012-02-23
- **Final completion:** 2012-02-23
- **Target enrollment:** 33 (ACTUAL)
- **Why stopped:** The trial was stopped due to the toxicities observed with the combination of pimasertib and temsirolimus.
- **Last updated:** 2018-07-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01378377

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01378377, "Combination Trial of Pimasertib (MSC1936369B) With Temsirolimus". Retrieved via AI Analytics 2026-05-31 from https://api.ai-analytics.org/clinical/NCT01378377. Licensed CC0.

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