# High-Dose Vorinostat and Fractionated Stereotactic Body Radiation Therapy in Treating Patients With Recurrent Glioma

> **NCT01378481** · PHASE1 · TERMINATED · sponsor: **National Cancer Institute (NCI)** · enrollment: 30 (actual)

## Conditions studied

- Adult Anaplastic Astrocytoma
- Adult Anaplastic Oligodendroglioma
- Adult Giant Cell Glioblastoma
- Adult Glioblastoma
- Adult Gliosarcoma
- Adult Mixed Glioma
- Recurrent Adult Brain Neoplasm

## Interventions

- **DRUG:** Vorinostat
- **RADIATION:** Stereotactic Radiosurgery
- **OTHER:** Laboratory Biomarker Analysis
- **OTHER:** Pharmacological Study
- **PROCEDURE:** Therapeutic Conventional Surgery

## Key facts

- **NCT ID:** NCT01378481
- **Lead sponsor:** National Cancer Institute (NCI)
- **Sponsor class:** NIH
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2012-06
- **Primary completion:** 2013-08
- **Final completion:** 2013-08
- **Target enrollment:** 30 (ACTUAL)
- **Last updated:** 2014-12-23


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01378481

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01378481, "High-Dose Vorinostat and Fractionated Stereotactic Body Radiation Therapy in Treating Patients With Recurrent Glioma". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT01378481. Licensed CC0.

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