Temsirolimus, Dexamethasone, Mitoxantrone Hydrochloride, Vincristine Sulfate, and Pegaspargase in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma

NCT01403415 · clinicaltrials.gov ↗

PHASE1

Phase

COMPLETED

Status

13

Enrollment

NIH

Sponsor class

Conditions

Childhood B Acute Lymphoblastic Leukemia
Childhood T Acute Lymphoblastic Leukemia
Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma
Recurrent Childhood Acute Lymphoblastic Leukemia
Recurrent Childhood Lymphoblastic Lymphoma

Interventions

DRUG: Dexamethasone
OTHER: Laboratory Biomarker Analysis
DRUG: Methotrexate
DRUG: Mitoxantrone Hydrochloride
DRUG: Pegaspargase
OTHER: Pharmacological Study
DRUG: Temsirolimus
DRUG: Vincristine Sulfate

Sponsor

National Cancer Institute (NCI)