# To Evaluate if Multiple Doses of Ketoconazole Change the Blood Concentration of YM150 (Darexaban)

> **NCT01405989** · PHASE1 · COMPLETED · sponsor: **Astellas Pharma Inc** · enrollment: 26 (actual)

## Conditions studied

- Pharmacokinetics of Darexaban and Metabolites
- Healthy Subjects

## Interventions

- **DRUG:** darexaban
- **DRUG:** ketoconazole

## Key facts

- **NCT ID:** NCT01405989
- **Lead sponsor:** Astellas Pharma Inc
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2010-01
- **Primary completion:** 2010-03
- **Final completion:** 2010-03
- **Target enrollment:** 26 (ACTUAL)
- **Last updated:** 2014-03-05


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01405989

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01405989, "To Evaluate if Multiple Doses of Ketoconazole Change the Blood Concentration of YM150 (Darexaban)". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT01405989. Licensed CC0.

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