# Effect of Metformin on Sensitivity of the GnRH Pulse Generator to Suppression by Estradiol and Progesterone

> **NCT01427595** · NA · COMPLETED · sponsor: **University of Virginia** · enrollment: 25 (actual)

## Conditions studied

- Polycystic Ovary Syndrome
- Hyperandrogenism

## Interventions

- **DRUG:** Metformin
- **DRUG:** Progesterone
- **DRUG:** estrace

## Key facts

- **NCT ID:** NCT01427595
- **Lead sponsor:** University of Virginia
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2009-02-18
- **Primary completion:** 2015-01-17
- **Final completion:** 2015-01-17
- **Target enrollment:** 25 (ACTUAL)
- **Last updated:** 2021-01-08

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01427595

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01427595, "Effect of Metformin on Sensitivity of the GnRH Pulse Generator to Suppression by Estradiol and Progesterone". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT01427595. Licensed CC0.

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