# A Study to Measure CSF Proteins in Elderly Healthy Volunteers and Volunteers With Mild Cognitive Impairment or Alzheimer's Disease

> **NCT01436188** · EARLY_PHASE1 · COMPLETED · sponsor: **Janssen Research & Development, LLC** · enrollment: 5 (actual)

## Conditions studied

- Healthy
- Alzheimer Disease

## Interventions

- **PROCEDURE:** Standard CSR sampling procedure
- **PROCEDURE:** Alternate frequency CSR sampling procedure
- **PROCEDURE:** Standard frequent CSR sampling procedure with 800 mg ibuprofen
- **PROCEDURE:** Standard CSR sampling procedure
- **PROCEDURE:** Alternative lower frequency CSR sampling procedure

## Key facts

- **NCT ID:** NCT01436188
- **Lead sponsor:** Janssen Research & Development, LLC
- **Sponsor class:** INDUSTRY
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2011-09
- **Primary completion:** —
- **Final completion:** 2013-06
- **Target enrollment:** 5 (ACTUAL)
- **Last updated:** 2014-03-18


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01436188

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01436188, "A Study to Measure CSF Proteins in Elderly Healthy Volunteers and Volunteers With Mild Cognitive Impairment or Alzheimer's Disease". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT01436188. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*