# Antioxidant Supplement and Reduction of Metachronous Adenomas of the Large Bowel: a Double Blind Randomized Trial

> **NCT01437826** · PHASE3 · TERMINATED · sponsor: **IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy** · enrollment: 411 (actual)

## Conditions studied

- Colorectal Adenomas

## Interventions

- **DRUG:** antioxidants
- **DRUG:** placebo

## Key facts

- **NCT ID:** NCT01437826
- **Lead sponsor:** IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 1988-03
- **Primary completion:** 1996-06
- **Final completion:** 1996-06
- **Target enrollment:** 411 (ACTUAL)
- **Why stopped:** 50% of eligible patients refused to enter the study
- **Last updated:** 2011-09-21

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01437826

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01437826, "Antioxidant Supplement and Reduction of Metachronous Adenomas of the Large Bowel: a Double Blind Randomized Trial". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT01437826. Licensed CC0.

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