# Effect of Duloxetine and Venlafaxine on the Pharmacokinetics and Pharmacodynamics of Oral Tramadol: A Three-phase Randomized Balanced Cross-over Study in Healthy Volunteers

> **NCT01443520** · PHASE4 · COMPLETED · sponsor: **Turku University Hospital** · enrollment: 12 (actual)

## Conditions studied

- Healthy

## Interventions

- **DRUG:** Placebo
- **DRUG:** Duloxetine
- **DRUG:** Venlafaxine

## Key facts

- **NCT ID:** NCT01443520
- **Lead sponsor:** Turku University Hospital
- **Sponsor class:** OTHER_GOV
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2011-10
- **Primary completion:** 2012-01
- **Final completion:** 2012-01
- **Target enrollment:** 12 (ACTUAL)
- **Last updated:** 2012-05-22


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01443520

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01443520, "Effect of Duloxetine and Venlafaxine on the Pharmacokinetics and Pharmacodynamics of Oral Tramadol: A Three-phase Randomized Balanced Cross-over Study in Healthy Volunteers". Retrieved via AI Analytics 2026-06-05 from https://api.ai-analytics.org/clinical/NCT01443520. Licensed CC0.

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