# Effectiveness of Fissure Sealant and Topical Fluoride Application in Preventing Dental Caries

> **NCT01446107** · NA · COMPLETED · sponsor: **The University of Hong Kong** · enrollment: 502 (actual)

## Conditions studied

- Dental Caries

## Interventions

- **OTHER:** placement of fissure sealant
- **OTHER:** fluoride varnish
- **OTHER:** silver fluoride
- **OTHER:** placebo control

## Key facts

- **NCT ID:** NCT01446107
- **Lead sponsor:** The University of Hong Kong
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2007-12
- **Primary completion:** 2010-12
- **Final completion:** 2010-12
- **Target enrollment:** 502 (ACTUAL)
- **Last updated:** 2021-05-03


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01446107

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01446107, "Effectiveness of Fissure Sealant and Topical Fluoride Application in Preventing Dental Caries". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT01446107. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*