# Treatment of Children With Kidney Transplants by Injection of CD4+CD25+FoxP3+ T Cells to Prevent Organ Rejection

> **NCT01446484** · PHASE1,PHASE2 · UNKNOWN · sponsor: **Pirogov Russian National Research Medical University** · enrollment: 30 (estimated)

## Conditions studied

- End-Stage Renal Disease
- Kidney Failure

## Interventions

- **BIOLOGICAL:** CD4+CD25+CD127lowFoxP3+ T regulatory cells injection
- **DRUG:** Alemtuzumab
- **DRUG:** Mycophenolate mofetil
- **DRUG:** Sirolimus
- **DRUG:** Tacrolimus
- **DRUG:** Cyclosporine
- **DRUG:** Everolimus
- **PROCEDURE:** Kidney transplantation

## Key facts

- **NCT ID:** NCT01446484
- **Lead sponsor:** Pirogov Russian National Research Medical University
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2011-10
- **Primary completion:** 2014-11
- **Final completion:** 2014-11
- **Target enrollment:** 30 (ESTIMATED)
- **Last updated:** 2011-11-18

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01446484

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01446484, "Treatment of Children With Kidney Transplants by Injection of CD4+CD25+FoxP3+ T Cells to Prevent Organ Rejection". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT01446484. Licensed CC0.

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