Effect of Sorafenib or Regorafenib on P63 Expression and Keratinocyte Differentiation in Human Skin

Stopped Accrual did not meet expectations. Over nearly 2 years just 4 subjects were treated on study. The goal of 30 subjects was not attainable.

Conditions

• Renal Cell Carcinoma
• Hepatocellular Carcinoma
• Colorectal Carcinoma

Interventions

• PROCEDURE: skin punch biopsy

Sponsor

Dartmouth-Hitchcock Medical Center