# Study of Heart Failure Hospitalizations After Aquapheresis Therapy Compared to Intravenous (IV) Diuretic Treatment

> **NCT01474200** · NA · TERMINATED · sponsor: **Nuwellis, Inc.** · enrollment: 224 (actual)

## Conditions studied

- Heart Failure
- Cardiac Failure
- Acute Decompensated Heart Failure (ADHF)

## Interventions

- **DEVICE:** Isolated veno-venous ultrafiltration (AQ)
- **DRUG:** IV Loop Diuretics (LD)

## Key facts

- **NCT ID:** NCT01474200
- **Lead sponsor:** Nuwellis, Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2012-01
- **Primary completion:** 2014-07
- **Final completion:** 2014-07
- **Target enrollment:** 224 (ACTUAL)
- **Why stopped:** Closed due to patient recruitment challenges. No interim analyses were completed; study closure was not related to any concerns about safety or futility.
- **Last updated:** 2023-08-29


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01474200

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01474200, "Study of Heart Failure Hospitalizations After Aquapheresis Therapy Compared to Intravenous (IV) Diuretic Treatment". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT01474200. Licensed CC0.

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