# Efficacy and Safety of TAK-875 Compared to Glimepiride When Used With Metformin in Participants With Type 2 Diabetes

> **NCT01481116** · PHASE3 · TERMINATED · sponsor: **Takeda** · enrollment: 2454 (actual)

## Conditions studied

- Diabetes Mellitus, Type 2

## Interventions

- **DRUG:** TAK-875
- **DRUG:** TAK-875
- **DRUG:** Glimepiride

## Key facts

- **NCT ID:** NCT01481116
- **Lead sponsor:** Takeda
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2012-01
- **Primary completion:** 2014-03
- **Final completion:** 2014-04
- **Target enrollment:** 2454 (ACTUAL)
- **Why stopped:** Due to potential concerns about liver safety (See Detailed Description)
- **Last updated:** 2016-06-01


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01481116

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01481116, "Efficacy and Safety of TAK-875 Compared to Glimepiride When Used With Metformin in Participants With Type 2 Diabetes". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT01481116. Licensed CC0.

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