# A Pilot Study of Decitabine and Vorinostat With Chemotherapy for Relapsed ALL

> **NCT01483690** · PHASE1,PHASE2 · TERMINATED · sponsor: **Therapeutic Advances in Childhood Leukemia Consortium** · enrollment: 23 (actual)

## Conditions studied

- Acute Lymphoblastic Leukemia
- Precursor B-Cell Lymphoblastic Leukemia
- Precursor T-Cell Lymphoblastic Leukemia

## Interventions

- **DRUG:** Decitabine
- **DRUG:** Vorinostat
- **DRUG:** Vincristine
- **DRUG:** Dexamethasone
- **DRUG:** Mitoxantrone
- **DRUG:** Pegaspargase
- **DRUG:** Methotrexate

## Key facts

- **NCT ID:** NCT01483690
- **Lead sponsor:** Therapeutic Advances in Childhood Leukemia Consortium
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2011-12
- **Primary completion:** 2015-07-31
- **Final completion:** 2015-07-31
- **Target enrollment:** 23 (ACTUAL)
- **Why stopped:** Toxicity
- **Last updated:** 2020-10-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01483690

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01483690, "A Pilot Study of Decitabine and Vorinostat With Chemotherapy for Relapsed ALL". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT01483690. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*