# An Open-label, Single-dose, Two-treatment, Randomized, Cross-over Study to Investigate the Effects of the SLCO2B1 c.1457C>T Polymorphism and Apple Juice on the Pharmacokinetics and Pharmacodynamics of Acebutolol in Healthy Korean and Japanese Volunteers

> **NCT01514019** · PHASE4 · COMPLETED · sponsor: **In-Jin Jang, MD, PhD** · enrollment: 16 (actual)

## Conditions studied

- Healthy

## Interventions

- **DRUG:** Acebutolol
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT01514019
- **Lead sponsor:** In-Jin Jang, MD, PhD
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2012-01
- **Primary completion:** 2012-05
- **Final completion:** 2012-05
- **Target enrollment:** 16 (ACTUAL)
- **Last updated:** 2012-06-20

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01514019

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01514019, "An Open-label, Single-dose, Two-treatment, Randomized, Cross-over Study to Investigate the Effects of the SLCO2B1 c.1457C>T Polymorphism and Apple Juice on the Pharmacokinetics and Pharmacodynamics of Acebutolol in Healthy Korean and Japanese Volunteers". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT01514019. Licensed CC0.

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