Veliparib, Radiation Therapy, and Temozolomide in Treating Younger Patients With Newly Diagnosed Diffuse Pontine Gliomas

NCT01514201 · clinicaltrials.gov ↗

PHASE1,PHASE2

Phase

COMPLETED

Status

66

Enrollment

NIH

Sponsor class

Conditions

Anaplastic Astrocytoma
Brain Stem Glioma
Childhood Mixed Glioma
Fibrillary Astrocytoma
Giant Cell Glioblastoma
Glioblastoma
Gliosarcoma
Untreated Childhood Anaplastic Astrocytoma
Untreated Childhood Brain Stem Glioma
Untreated Childhood Fibrillary Astrocytoma
Untreated Childhood Giant Cell Glioblastoma
Untreated Childhood Glioblastoma
Untreated Childhood Gliosarcoma

Interventions

RADIATION: 3-Dimensional Conformal Radiation Therapy
RADIATION: Intensity-Modulated Radiation Therapy
OTHER: Laboratory Biomarker Analysis
OTHER: Pharmacological Study
DRUG: Temozolomide
DRUG: Veliparib

Sponsor

National Cancer Institute (NCI)