# Intergroup Randomized Trial for Children or Adolescents With B-Cell Non Hodgkin Lymphoma or B-Acute Leukemia: Rituximab Evaluation in High Risk Patients

> **NCT01516580** · PHASE3 · COMPLETED · sponsor: **Gustave Roussy, Cancer Campus, Grand Paris** · enrollment: 482 (actual)

## Conditions studied

- B-cell Non Hodgkin Lymphoma
- Mature B-cell Leukemia Burkitt-type

## Interventions

- **DRUG:** Vincristine, cyclophosphamide, methotrexate, doxorubicin, cytarabine, ara-C
- **DRUG:** Rituximab, Vincristine, cyclophosphamide, methotrexate, doxorubicin, cytarabine, ara-C

## Key facts

- **NCT ID:** NCT01516580
- **Lead sponsor:** Gustave Roussy, Cancer Campus, Grand Paris
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2011-12
- **Primary completion:** 2017-06-13
- **Final completion:** 2022-11-16
- **Target enrollment:** 482 (ACTUAL)
- **Last updated:** 2026-02-09

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01516580

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01516580, "Intergroup Randomized Trial for Children or Adolescents With B-Cell Non Hodgkin Lymphoma or B-Acute Leukemia: Rituximab Evaluation in High Risk Patients". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT01516580. Licensed CC0.

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