# Pre-therapeutic Identification of Dihydropyrimidine Dehydrogenase Gene (DPD) Deficiency for Predicting Toxicity to Fluoropyrimidines

> **NCT01547923** · NA · TERMINATED · sponsor: **Institut Cancerologie de l'Ouest** · enrollment: 1142 (actual)

## Conditions studied

- Colorectal Cancer
- Intravenous 5 Fluorouracile

## Interventions

- **GENETIC:** Blood sample for phenotypic and pharmacogenetic analysis.
- **GENETIC:** Blood sample for phenotypic and pharmacogenetic analysis.

## Key facts

- **NCT ID:** NCT01547923
- **Lead sponsor:** Institut Cancerologie de l'Ouest
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2008-06-16
- **Primary completion:** 2013-03
- **Final completion:** 2013-03-04
- **Target enrollment:** 1142 (ACTUAL)
- **Why stopped:** The study stopped due to a death in the arm control
- **Last updated:** 2020-03-25


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01547923

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01547923, "Pre-therapeutic Identification of Dihydropyrimidine Dehydrogenase Gene (DPD) Deficiency for Predicting Toxicity to Fluoropyrimidines". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT01547923. Licensed CC0.

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