# Device Closure Versus Medical Therapy for Cryptogenic Stroke Patients With High-Risk Patent Foramen Ovale (DEFENSE-PFO)

> **NCT01550588** · PHASE4 · UNKNOWN · sponsor: **Jae-Kwan Song** · enrollment: 210 (estimated)

## Conditions studied

- Patent Foramen Ovale

## Interventions

- **DEVICE:** Device closure
- **DRUG:** Standard medical treatment

## Key facts

- **NCT ID:** NCT01550588
- **Lead sponsor:** Jae-Kwan Song
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2012-02
- **Primary completion:** 2020-02
- **Final completion:** 2020-02
- **Target enrollment:** 210 (ESTIMATED)
- **Last updated:** 2017-06-29


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01550588

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01550588, "Device Closure Versus Medical Therapy for Cryptogenic Stroke Patients With High-Risk Patent Foramen Ovale (DEFENSE-PFO)". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT01550588. Licensed CC0.

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