Oxaliplatin, Fluorouracil, Erlotinib Hydrochloride, and Radiation Therapy Before Surgery and Erlotinib Hydrochloride After Surgery in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction
Conditions
- Adenocarcinoma of the Esophagus
- Adenocarcinoma of the Gastroesophageal Junction
- Adenocarcinoma of the Stomach
- Squamous Cell Carcinoma of the Esophagus
- Stage II Esophageal Cancer
- Stage II Gastric Cancer
- Stage III Esophageal Cancer
- Stage III Gastric Cancer
Interventions
- DRUG: erlotinib hydrochloride
- DRUG: oxaliplatin
- DRUG: fluorouracil
- RADIATION: radiation therapy
- PROCEDURE: conventional surgery
- OTHER: immunohistochemistry staining method
- PROCEDURE: positron emission tomography
- PROCEDURE: computed tomography
- PROCEDURE: laboratory biomarker analysis
- GENETIC: gene expression analysis
- RADIATION: fludeoxyglucose F 18
Sponsor
Wake Forest University Health Sciences
Collaborators